Pharm Ingredients
Zinc L Carnosine (Polaprezinc) Powder
Zinc L Carnosine (Polaprezinc) Powder Manufacturers
Kintainutri® supplies zinc L carnosine (polaprezinc) powder with a purity of 99%. Zinc L carnosine is a chelate formed by zinc and L-carnosine in a 1:1 molar ratio, L-carnosine itself is a dipeptide composed of beta-alanine and L-histidine, possessing antioxidant properties as well as the ability to scavenge free radicals and chelate metal ions. Upon chelation, polaprezinc powder combines the mucosal-repairing properties of zinc with the anti-inflammatory and antioxidant functions of L-carnosine, while also exhibiting a high affinity for damaged tissues.
Kintainutri®’s polaprezinc powder appears as a white powder that is odorless or possesses only a faint characteristic odor, with a slightly bitter taste. It exhibits excellent water solubility, dissolving readily in water to form a neutral to slightly acidic solution. Kintainutri®’s polaprezinc is suitable for applications in functional foods, dietary supplements, and pharmaceutical raw materials. We offer direct-from-factory supply and can provide full compliance documentation, including COAs and MSDSs, inquiries are warmly welcomed.
| Product Name | Source | Best-selling Specifications |
|---|---|---|
| Zinc L Carnosine (Polaprezinc) Powder | Synthesis | |
| 98% | ||
| 99% |
| Items | Specifications | Results |
|---|---|---|
| Appearance | White powder | Conforms |
| Color | White to almost white | Conforms |
| Smell | Odourless | Conforms |
| Identification | Must comply | Conforms |
| Loss on drying | ≤1.0% | 0.09% |
| Heavy Metals | ≤10ppm | <10ppm |
| Arsenic | ≤1ppm | <1ppm |
| Lead | ≤2ppm | <2ppm |
| Cadmium | ≤1ppm | <1ppm |
| Mercury | ≤0.1ppm | <0.1ppm |
| Specific Rotation | +20° to +22° | 20.8° |
| Residue on Ignition | ≤0.10% | 0.1% |
| Melting Point | 250-265℃ | Conforms |
| PH(in 2% water) | 7.5-8.5 | 8.3 |
| L-histidine | ≤1.0% | <1.0% |
| β-alanine | ≤0.1% | <0.1% |
| Total aerobes counts | 1000 CFU/g max | <10 CFU/g |
| Mold & Yeast | 100 CFU/g max | <10 CFU/g |
| E.Coli | Negative | Not Detectable |
| Salmonella | Negative | Not Detectable |
| Hydrazine content | Not Detectable | Not Detectable |
| Particle Size | 100% through 100 mesh | Conforms |
| Loose Bulk Density | ≥0.20g/ml | 0.25g/ml |
| Assay | 99.0%~101.0% | 99.7% |
How To Make Zinc L Carnosine (Polaprezinc) Powder?
Zinc L Carnosine (Polaprezinc) Powder Benefits
Zinc L Carnosine Gastritis
Polaprezinc powder is a scientifically studied ingredient recognized for its supportive effects on gastrointestinal mucosal health. Research suggests that it may accelerate the healing of gastric ulcers, with endoscopic healing rates reported to exceed 60% within eight weeks in certain studies. Its protective effects on the gastric mucosa are primarily associated with anti-inflammatory and antioxidant activities. In addition, zinc L-carnosine powder may help reduce gastrointestinal damage induced by nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, support the eradication of Helicobacter pylori, and alleviate oral mucositis associated with chemotherapy and radiotherapy. Kintainutri®’s zinc L carnosine (polaprezinc) powder can be used as a functional ingredient in formulations designed to support gastrointestinal mucosal health.
Supports gastrointestinal barrier function
Chronic gastric discomfort typically manifests as acid reflux and gastroesophageal reflux disease (GERD). Conventional antacids merely neutralize stomach acid temporarily but fail to repair underlying tissue damage. Bulk zinc L-carnosine powder offers a root-cause solution for anti-reflux formulations. It forms a protective barrier over inflamed gastric mucosa, buffering the impact of excess stomach acid and providing sustained relief from reflux and burning sensations, all without disrupting healthy digestive function.
Anti-inflammatory medications can lead to increased intestinal permeability (commonly known as "leaky gut"), a condition that carnosine zinc complexcan completely prevent. In a human clinical trial, intestinal permeability increased threefold following the administration of anti-inflammatory drugs. However, the group that simultaneously took L-carnosine zinc showed no such abnormalities. Furthermore, zinc carnosine may promote the migration and proliferation of damaged intestinal cells, thereby supporting the intestinal repair process. Research suggests that polaprezinc powder may help protect the small intestine and could be particularly relevant for individuals with long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin or ibuprofen.
Antioxidant protection properties
Both hydrogen peroxide (H₂O₂) and ethanol can induce dose-dependent cellular damage, whereas zinc L-carnosine powder exerts a direct antioxidant protective effect. Upon the addition of zinc L-carnosine, the H₂O₂- and ethanol-induced release of ⁵¹Cr was significantly inhibited, and the dose-response curves shifted markedly to the right. Furthermore, polaprezinc powder was also found to inhibit ethanol-induced superoxide anion generation (as indicated by the reduction of cytochrome c), thereby confirming its cytoprotective efficacy. Through its direct antioxidant activity, polaprezinc may help protect gastric mucosal cells from damage induced by harmful factors, including oxidative stress and ethanol exposure.
What Is Zinc L Carnosine (Polaprezinc) Powder Used For?
Zinc L carnosine supplement
Zinc complexes (ZnC), which are currently marketed as over-the-counter dietary supplements, exhibit biological activity and have been reported to support multiple aspects of intestinal mucosal integrity. As a functional ingredient, ZnC can be incorporated into health supplements designed for individuals experiencing gastric discomfort, excessive stomach acidity, or those requiring gastric mucosal maintenance, thereby providing daily protection and support.
Furthermore, as a key endogenous antioxidant enzyme, the metabolic products of HO-1 exert profound anti-inflammatory, antioxidant, and cytoprotective effects. This advanced molecular mechanism substantiates the high efficacy of Zinc Carnosine in formulations targeting GERD and intestinal barrier health, providing supplement brands with a solid scientific foundation for utilizing this premium ingredient in functional foods and dietary supplements.
Gastrointestinal health formulas
Polaprezinc (L-carnosine zinc) is widely utilized in the medical field, possessing anti-inflammatory, antioxidant, and heat shock protein-inducing properties. Its primary application lies in promoting the healing of gastric ulcers and serving as an adjunct to triple therapy for the eradication of Helicobacter pylori (potentially increasing the eradication rate by approximately 18%). Furthermore, it effectively prevents oral mucositis, radiation esophagitis, and gastroenteritis induced by radiotherapy and chemotherapy, mitigates small intestinal injury caused by low-dose aspirin; alleviates taste disorders, and demonstrates potential in the treatment of ulcerative colitis and hepatic fibrosis.
Zinc L Carnosine (Polaprezinc) Powder Dosage And Safety
Zinc L-Carnosine (Polaprezinc) has demonstrated a favorable safety profile. In animal studies, only mild reactions, such as salivation, were observed at high doses (≥300 mg/kg). Additionally, no serious adverse events have been reported during long-term use at standard clinical dosages (150 mg/day, providing approximately 15–16 mg of elemental zinc). In human studies, the most commonly reported side effects include occasional gastrointestinal symptoms, such as nausea and constipation, which are generally transient in nature.
Note: Concomitant administration with D-penicillamine or levothyroxine sodium may interfere with absorption; therefore, it is recommended to take these medications at separate times. This product has been approved in Japan for the treatment of gastric ulcers; based on extensive clinical experience and numerous studies, its safety is well-established and reliable, making it suitable for use as an ingredient in functional foods and dietary supplements.
Where To Buy Zinc L Carnosine (Polaprezinc) Powder?
Kintainutri® is your trusted global B2B supply partner. We specialize in producing high-quality Zinc L-Carnosine powder with a purity exceeding 98%, strictly adhering to GMP standards. We offer highly competitive wholesale pricing, flexible MOQ customization, and a stable supply chain. Contact Kintainutri today to request free samples and authoritative test reports—we look forward to partnering with you!
*Kintainutri® Promise All Products: Non-Irradiated / Non-ETO/ Treat by Heat Only / Non-GMO
FAQ
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How long does zinc L-carnosine powder take to work?
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Is zinc L-carnosine powder the same as polaprezinc?
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Does zinc L-carnosine powder support stomach health?
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